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dc.contributor.authorMellqvist Fässberg, Madeleine
dc.date.accessioned2014-05-23T12:13:10Z
dc.date.available2014-05-23T12:13:10Z
dc.date.issued2014-05-23
dc.identifier.isbn978-91-628-9057-5
dc.identifier.urihttp://hdl.handle.net/2077/35461
dc.description.abstractOlder adults have high rates of suicide, and the strong role of depression is often emphasized in studies on suicidal behaviour in this age group. The literature regarding other factors is rather sparse. This thesis utilizes data from three population-based studies and one clinical study with the aim of increasing knowledge about factors associated with suicidal behavior in late life. Study I is based on data from EURODEP, a multicenter study involving 15,890 adults (9,429 women, 6461 men) aged 64-104 years. In Study II, all 97-year-olds living in Gothenburg were invited to take part and 269 (197 women, 72 men) without dementia participated. The Prospective Population Study on Women, initiated in 1968, provided data for study III; 800 middle-aged women were examined in 1968 and followed over a 42-year period. In Study IV a hospital cohort of 80 individuals (42 women, 38 men) aged 70-91 were interviewed after a suicide attempt. Findings from study I showed that both intermediate and high functional disability was associated with death wishes in both sexes. Results remained after adding depressive symptoms to the model. Among the 97-year-olds in study II, 11.5 % reported suicidal feelings in accordance with the Paykel questions and the majority (77.4 %) of these fulfilled criteria for neither major nor minor depression. Sleep problems and deficient social contacts were associated with suicidal feelings; relationships were independent of depression. One fourth of the women who participated in study III had experienced suicidal thoughts at some point during their life and 8 % had made at least one suicide attempt. Onset of suicidal behavior occurred after age 40 in half the women. Women who reported five or more early childhood adversities were significantly younger when they had their first-episode of suicidal thoughts. In study IV a strong association between major depression and low Sense of Coherence (SOC) was observed. Low SOC was associated with deficient social contacts and having moved in the past five years, and these relationships remained also after adjustment for depression. While early detection and treatment of depression is imperative, interventions to reduce suicidal behavior in later life may also need to target functional disability, pain and sleep problems, and limited social networks.sv
dc.language.isoengsv
dc.relation.haspartI. Fässberg, M.M., Östling, S., Braam, A.W., Bäckman, K., Copeland, J.R.M., Fichter, M., Kivelä, S-L., Lawlor, B.A., Lobo, A., Magnússon, H., Prince, M.J., Reischies, F.M., Turrina, C., Wilson, K., Skoog, I., Waern, M. Functional Disability and Death Wishes in older Europeans: Results from the EURODEP Concerted Action. Social Psychiatry and Psychiatric Epidemiology. 2014 Feb 20. ::PMID::24554123sv
dc.relation.haspartII. Fässberg, M.M., Östling, S., Börjesson-Hanson, A., Skoog, I., Waern, M. Suicidal feelings in the twilight of life: A cross-sectional population-based study of 97-year-olds. BMJ Open. 2013 Feb 1;3(2). Print 2013. ::doi::10.1136/bmjopen-2012-002260sv
dc.relation.haspartIII. Fässberg, M.M., Joas, E., Hällström, T., Östling, S., Gustafson, D., Wiktorsson, S., Kaplan, M., Hawton, K., Skoog, I., Waern, M. Suicidal thoughts and attempts in a population-based sample of women followed over 42 years: The influence of early life adversity. In manuscript.sv
dc.relation.haspartIV. Mellqvist, M., Wiktorsson, S., Joas, E., Östling, S., Skoog, I., Waern, M. Sense of coherence in elderly suicide attempters: The impact of social and health-related factors. International Psychogeriatrics. 2011 Aug; 23(6):986-93. Epub 2011 ::doi::10.1017/S1041610211000196sv
dc.subjectOlder adultssv
dc.subjectDeath wishessv
dc.subjectSuicidal feelingssv
dc.subjectSuicidal thoughtssv
dc.subjectSuicide attemptsv
dc.subjectFunctional disabilitysv
dc.subjectSocial factorssv
dc.subjectEarly childhood adversitysv
dc.subjectSense of Coherencesv
dc.titleSuicidal behavior in late life: population and patient perspectivessv
dc.typetexteng
dc.type.svepDoctoral thesiseng
dc.gup.mailmadeleine.mellqvist@neuro.gu.sesv
dc.type.degreeDoctor of Philosophy (Medicine)sv
dc.gup.originUniversity of Gothenburg. Sahlgrenska Academysv
dc.gup.departmentInstitute of Neuroscience and Physiology. Department of Psychiatry and Neurochemistrysv
dc.gup.defenceplaceFredagen den 13 juni 2014, kl. 9.00, Hörsal Ivan Östholm, Medicinaregatan 13sv
dc.gup.defencedate2014-06-13
dc.gup.dissdb-fakultetSA


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