Examensarbete 30 Hp, Läkarprogrammet: Recent submissions
Now showing items 121-140 of 388
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The effect of the APOE genotype on Alzheimer´s pathology in pathological ageing and Alzheimer´s disease
(2020-09-28)Background: The pathological hallmarks of Alzheimer's disease (AD) are amyloid-P (AP) plaques and neurofibrillary tau tangles. The APOE E4-allele is the most important genetic risk factor behind AD and has been linked to ... -
Mechanism of Action of the Glucagon-like Peptide-1 analog Exendin-4 in the Reward System – A Preclinical Study in the Drug Addiction Field
(2020-09-28)Background: Alcohol use disorder is a great concern for public health and current pharmacological treatment is not sufficient. Over the last years, there has been a growing interest in the role of gut hormones in drug ... -
Conversion from Laparoscopic to Open Surgery in Colorectal Cancer Patients at Colombo South Teaching Hospital, Sri Lanka
(2020-09-28)Degree Project, Programme in Medicine, “Conversion from Laparoscopic to Open Surgery in Colorectal Cancer Patients at Colombo South Teaching Hospital, Sri Lanka” by Hedvig Bengtsson, The Sahlgrenska Academy, University ... -
Chronic Back Pain and Widespread Pain – associations with Quality of life
(2020-09-28)Background Pain is common, both as acute and as chronic (long-lasting more than 3 months). Acute pain is normally treated effectively, chronic pain though has a poor prognosis. Chronic pain has a high prevalence, both ... -
From bystanders to immediate responders – how to enable civilians to respond to mass casualties
(2020-09-28)Background The number of prehospital deaths due to accidental injuries are high, and might be preventable if bystanders are prepared and could act quickly during the gap in time from incident to the arrival of the Emergency ... -
Modeling the effect of hypoxic conditions on the IFNg secretion by adoptively transferred T cells
(2020-09-28)Adoptive cell therapy (ACT) with tumor-infiltrating T lymphocytes (TIL) is transfusion of T cells derived from patients’ biopsies after enhancing their function in vitro. It is currently in clinical trials for several ... -
Mitochondrial dysfunction in juvenile and adult dermatomyositis
(2020-09-28)Introduction Previous studies have shown perifascicular regions in dermatomyositis with mitochondrial abnormalities affecting complex IV also known as cytochrome c oxidase (COX) in the respiratory chain. The aim of this ... -
Enhanced retention of protein damage during ageing
(2020-09-28)Age can be reset in many different cell types through asymmetric cell division. During such a division, retention of aging factors in one cell allows the rejuvenation of the other. In unicellular organisms, it can provide ... -
Immune Checkpoint Receptor Expression in NK Cells
(2020-09-28)Background Immunotherapy for cancer has improved overall survival and revolutionized the field of oncology. Blockade of immune checkpoint receptors has reversed cancer-induced inhibition of T cells and natural killer ... -
Clinical outcome of postchemotherapy retroperitoneal lymph node dissection in advanced nonseminomatous germ cell tumors
(2020-09-28)Background: Nonseminomatous germ cell tumors (NSGCT) which have not responded adequately to chemotherapy requires subsequent surgical removal of the residual tumor (post chemotherapy retroperitoneal lymph node dissection, ... -
Targeted therapy in metastaical melanoma: Clinical evaluation and biomarkers for response
(2020-09-28)BRAF-MEK-inhibition and real world data in metastatic melanoma: Clinical evaluation and biomarkers for response Degree project, programme in medicine, 2018 Christoffer Kvarnström Supervisors: Lars Ny and Henrik Jespersen ... -
A Methodological Study Comparing Two Motor Cortex Plasticity Paradigms in Healthy Adults
(2020-09-28)Background: Neural plasticity is an important function of the brain allowing for change in synaptic transmissions. Modulation in plasticity arises through activity-dependent strengthening; long-term potentiation (LTP), or ... -
Maternal and infant body composition in relation to fish and meat intake during pregnancy - A randomized longitudinal dietary intervention study
(2020-09-23)Introduction: Many women start their pregnancy at a high BMI and gain more weight than recommended during pregnancy, thus increasing the risk for severe pregnancy complications and children born large for gestational ... -
50 år av Hemoglobinnivåer hos kvinnor i Kvinnoundersökningen 1968-1969 till 2016-2017
(2020-09-23)Introduction: Anemia is a global problem and women and children are the most affected. The symptoms of anemia are for example tiredness, dyspnea and headache. Previous studies of trends of anemia over time have not been ... -
Gramnegativ sepsis hos barncancerpatienter i Göteborg; kliniska aspekter
(2020-09-23)Background: Children with cancer or children after stem cell transplantation have an increased risk of neutropenic infections. Previous studies have shown that the incidence of gram-negative bacteraemia has increased in ... -
Completeness of Proximal Humeral Fracture Reoperation
(2020-09-22)Background: The Swedish Fracture Register (SFR) was started in 2011 at Sahlgrenska University Hospital (SUH). Since then, proximal humeral fractures (PHF) have been consecutively registered. Reoperation is considered a ... -
Fever in infants below 2 months of age: clinical management and outcome
(2020-09-22)Title: Fever in infants below 2 months of age: clinical management and outcome Degree Project in Medicine, Programme in Medicine, Sahlgrenska Academy at the University of Gothenburg, Sweden 2019. Author: Michelle Bäckman ... -
Associations between ECG abnormalities and death or myocardial infarction. A 25 year follow up of middle-aged men employed in a Swedish automotive industry
(2020-09-22)Background: The Coeur Project started in 1992 as a joint medical project between two automotive companies, one located in Sweden (the Volvo Corporation) and one located in France (Renault Automotive Group). The original ... -
Long-Term Outcomes of Percutaneous Radiofrequency Ablation of Small Renal Tumours
(2020-09-22)Background: Ablation technique is relatively new nephron-sparing treatment of small renal masses (SRM). It carries a lower complication rate and lower overall healthcare costs compared with surgery. However, there are ... -
Risk Factors for Harmful Alcohol Consumption Among University Students in Hanoi
(2020-09-22)Background: Excessive alcohol consumption is a risk factor for many non-communicable diseases and is considered an important target in reaching the sustainable development goals set by the UN. In Vietnam, alcohol consumption ...