Doctoral Theses from Sahlgrenska Academy: Recent submissions
Now showing items 101-120 of 2013
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Blood and Bone - Epidemiological studies on the association between blood and bone
(2021-05-07)Introduction: Preclinical and clinical studies have suggested that blood- and bone cells are interconnected. Aims: To study the association between hematological variables, specifically serotonin, erythropoietin (EPO), ... -
Recidivism and Static-99R risk assessments in a Swedish cohort of mentally disordered sexual offenders
(2021-05-07)Mentally disordered sexual offenders (MDSOs) constitute a heterogeneous offender subgroup presenting a wide range of clinical comorbidity. The recidivism rates for such a disparate subgroup vary substantially, which ... -
Optimized use of MRI in a PSA based prostate cancer screening program
(2021-05-07)The overall aim of this thesis was to optimize different aspects of the use of MRI in screening for prostate cancer. Paper 1 was based on preoperative MRI in a prostatectomy cohort. Papers 2-4 were based on data from the ... -
Methodological considerations in epidemiological studies in perinatal medicine
(2021-05-05)This thesis is based on two projects, each consisting of two papers. In these two projects we investigated factors affecting the variability in gestational duration, and associations between maternal diet and neonatal ... -
Women’s health in midlife - a person-centered approach in primary care -effects on mental, somatic, and urogenital symptoms, and quality of life.
(2021-05-05)Midlife women, from 45-60, enter new challenges in life with various impacts on health and quality of life. Mental and stress-related illnesses are common causes for attending primary health care (PHC) and long-term sick ... -
Pituitary Tumor Surgery - factors influencing outcome
(2021-05-05)Background: Pituitary tumors represent 15–20% of intracranial tumors. The majority are benign adenomas, of which 30 % are hormonally inactive, the non-functioning pituitary adenomas (NFPAs). A possible neuronal damage ... -
Body weight, body size and early cardiovascular disease. Epidemiological studies using Swedish registries
(2021-05-04)Background: Obesity is a known risk factor for cardiovascular morbidity and mortality, as well as for atrial fibrillation and heart failure. While overweight and obesity have become increasingly more common in Sweden and ... -
Transurethral microwave thermotherapy and transurethral resection of the prostate. Evaluation and development.
(2021-04-29)ABSTRACT Lower urinary tract symptoms (LUTS) are common among men and become more prevalent with increasing age. One frequent cause is benign prostatic obstruction (BPO). Patients with LUTS/BPO can be ameliorated if the ... -
Prolonged mechanical ventilation in Swedish intensive care units: patient characteristics, prevalence, weaning and challenges in care
(2021-04-27)The overall aim of this thesis was to explore the care of adult patients on prolonged mechanical ventilation (PMV) in Swedish intensive care units (ICUs). Secondary aims were to identify the prevalence, characteristics and ... -
Heart Failure and Aortic Stenosis - Factors Influencing Prognosis and Development
(2021-04-27)Background: An ageing population increases the prevalence of heart failure (HF) and aortic stenosis (AS). Several studies have investigated prognosis and predictors of HF with preserved ejection fraction (HFpEF) compared ... -
Childhood overweight and pubertal timing as predictors of adult cancer in men
(2021-04-27)Background and Aim Obesity is one of the leading causes of cancer globally. The importance of overweight in childhood for adult cancer risk, independent of overweight status in young adulthood is still unknown. Furthermore, ... -
Cerebrospinal fluid biomarkers and cognition in older adults
(2021-04-21)Alzheimer’s disease (AD) is the most common type of dementia. The cause of the disease is unknown, but a substantial amount of evidence suggest that the disease is started by an imbalance in the production and clearance ... -
Magnetic Resonance Imaging as a Screening Tool for Prostate Cancer
(2021-04-20)The overall aim of this thesis was to explore the role of Magnetic resonance imaging (MRI) of the prostate as an adjunct to the prostate-specific antigen (PSA)-test in screening for prostate cancer (PCa), focusing on the ... -
Multiple primary malignancies in breast cancer patients. From population study to genetics
(2021-04-16)Breast cancer (BC) is one of the most common causes of cancer-related death among women worldwide. Due to early detection of BC and more tailor-made treatments, patients live longer despite their illness. Studies have shown ... -
Iodine intake and uptake in populations at risk for iodine deficiency
(2021-04-16)Background: Iodine is essential for the production of thyroid hormones. Both iodine deficiency (ID) and iodine excess may be harmful. Iodine intake in Sweden is considered adequate for the general population due to iodization ... -
Robotic Surgery for Endometrial Cancer
(2021-04-16)Endometrial cancer (EC) is the most common gynecological malignancy. A large proportion of patients present with the risk factors high age and obesity, which puts them at increased risk when undergoing surgery. The last ... -
Cell Therapy in lntervertebral Disc Degeneration
(2021-04-12)Background: Chronic low back pain (LBP) is the leading cause of disability worldwide. Intervertebral disc degeneration (IDD) is central in the pathogenesis. The injection of bone marrow-derived mesenchymal stromal cells ... -
Young adults with childhood-onset inflammatory bowel disease - aspects of bone mineral density, body composition and physical exercise
(2021-04-07)Background: Our research group has previously shown that low bone mineral density (BMD) is common in children and adolescents with inflammatory bowel disease (IBD). However, there is limited knowledge on the development ... -
Neuropsychological outcomes and health-related quality of life of children operated for nonsyndromic craniosynostosis
(2021-04-06)The primary aim of this thesis was to assess the intelligence quotient, attention function, adaptive behavior skills, and health-related quality of life of children operated for nonsyndromic craniosynostosis. The secondary ... -
Assessment of neurological prognosis after cardiac arrest – clinical and neurophysiological aspects
(2021-04-06)Background: Post-resuscitation care after cardiac arrest in adults includes targeted temperature management (TTM) to mitigate secondary brain injury. The recommended target temperature is between 32°C and 36°C after a ...