Visar i datumordning:
Visas titlar 1-20 av 570
-
Medication adherence, side effects and patient-physician interaction in hypertension
(2006)Hypertension is an important risk factor for cardiovascular disease, the incidence of which it is possible to reduce by prophylactic treatment with antihypertensive drugs. In clinical practice, however, only a minority of ... -
Medical problems associated with spinal cord lesions - impact on functioning
(2006-09-01)Aims: The overall aim of this thesis was to study the effects of medical problems associated with spinal cord lesions on functioning - with special interest in work participation and sexual functioning. A special aim was ... -
Membrane Proteins in Human Neutrophils - Identification and Characterization of Lipid Rafts in Subcellular Organelles
(2006-09-29)The human neutrophil is an important effector cell in acute inflammation and in the innate immune response against bacteria and fungi. When immune reactions occur in the tissue in response to antigen challenge, neutrophils ... -
Role of GPIbαlpha Clustering and N-linked Carbohydrates in the Clearance of Refrigerated Platelets
(2006-10-06)The thesis focuses on understanding the mechanisms by which: 1) the macrophage alphaM-subunit recognizes betaN-acetylglucosamine (betaGlcNAc) residues on the von Willebrand factor receptor complex ((GPIbalpha,beta/IX)2V ... -
Swedish Pharmaceutical Benefit Reforms - Analyses of implementation, pharmaceutical sales patterns and expenditures
(2006-10-24)Background: Over the last few decades, the sales of prescription drugs have increased dramatically in many western countries; however, this increase requires individuals and society to bear larger economic consequences. ... -
Endogenous t-PA release and pharmacological thrombolysis - Experimental animal studies of the coronary circulation
(2006-10-25)Abstract The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA) released from endothelial cells. In man, sympathomimetic drugs increase the systemic concentration ... -
Vitamin B12 and folate depletion in the elderly Diagnosis, clinical correlates and causes
(2006-11-10)Subclinical vitamin B12 and folate deficiency is common in the elderly. The clinical significance remains unresolved. There is not a universally accepted set of laboratory criteria for diagnosis, however subclinical ... -
Myocardial metabolism and ischemia assessed by microdialysis. Clinical and experimental studies in cardiac surgery
(2006-11-23)Background: The available methods to study myocardial metabolism and ischemia show considerable limitations when employed during and after cardiac surgery. Microdialysis is a technique for continuous sampling of substances ... -
Caring in research and practice - some nursing aspects
(2006-12-19)Caring in research and practice - some nursing aspects Siv Bäck-Pettersson Institute of Medicine, Department of Public Health and Community Medicine/Primary Health Care, The Sahlgrenska Academy at Göteborg University, ... -
Acute Coronary Syndromes. Characteristics, management and prognosis in relation to gender and type of syndrome
(2006-12-20)ABSTRACT Background: Acute coronary syndromes (ACS) represent a wide spectrum of conditions from ST-elevation myocardial infarction (STEMI) to unstable angina pectoris (UAP). Randomized trials tend to focus on ST-elevation ... -
Interleukin-17 in models of neutrophilic lung disease
(2006-12-20)Several acute or chronic lung disorders like adult respiratory distress syndrome, acute severe asthma, chronic obstructive pulmonary disease, chronic lung allograft rejection and cystic fibrosis, are associated with signs ... -
Storage organelles that are distinct from the classical granules in human neutrophils
(2006-12-27)The human neutrophil is a crucial participant in acute inflammation. Appropriate immune response is dependent on rapid direction of phagocytic cells through the tissue, towards the inflammatory focus. Such movement is ... -
Immune regulation of herpes simplex virus type 2 infection: Special emphasis on the transcription factor T-bet
(2007-01-03)Herpes simplex virus type 2 (HSV-2) is a sexually transmitted pathogen that infects the genital tract mucosa as well as local sensory neurons. It is the most common cause of genital ulcer disease in humans. The infection ... -
Läkemedel och följsamhet - Studier ur ett allmänmedicinskt perspektiv
(2007-02-02)The thesis is based on four studies illuminating from different perspectives the problem of compliance with medication. The research arises from the fact that more and more drugs are prescribed to patients thereby leading ... -
Proteases in Staphylococcal Arthritis
(2007-02-06)Proteases in Staphylococcal Arthritis Ann-Marie Calander Department of Rheumatology and Inflammation Research, Sahlgrenska Academy, Göteborg University, Guldhedsgatan 10A, 413 46 Göteborg, Sweden Staphylococcus ... -
Immunomodulation by estrogen and estren
(2007-03-02)Estrogen affects the development and regulation of the immune system. Treatment of gonadectomized mice with estrogen results in suppression of T and B lymphopoiesis, as well as decreased delayed type hypersensitivity ... -
Elemental composition of fine particles: exposure in the general population and influence from different sources
(2007-03-02)The general population is exposed to particulate air pollution from many different local and regional sources. Examples of local sources are traffic, biomass burning and resuspended dust, while regional sources are ... -
Characteristics and Processes of Treatment Seeking for Alcohol Problems -findings from epidemiological and qualitative studies
(2007-03-06)Background: Alcohol use and misuse are related to several physical, mental, and social harms in Sweden. Early identification of risky alcohol consumption followed by appropriate intervention can lead to decreased alcohol ... -
Overweight and obesity in the young and old: Prevalence, prevention and eating behavior
(2007-03-09)ABSTRACT Background: During the last 25 years the prevalence of overweight and obe-sity has increased dramatically, both in developed and developing countries. The World Health Organization is declaring it an epidemic. ... -
The Role of Gut Dysfunction and Nutritional Factors in Liver Cirrhosis
(2007-03-14)Malnutrition is a common finding in patients with liver cirrhosis. Malnutrition has been shown to be associated with increased morbidity and mortality. Its pathogenesis remains unclear but both poor dietary intake and ...