Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för medicin by Title
Now showing items 1-20 of 570
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A gender perspective on irritable bowel syndrome: symptoms, experiences and the development of a person-centred support intervention
(2016-11-10)Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder which affects approximately ten percent of the world’s population and which is more prevalent among women than men. The hallmark symptoms of ... -
A prevention and health promotion programme for persons with overweight in Primary Health Care Patient outcomes and nurses’ experiences in terms of weight, lifestyle, health and risk factors
(2020-11-20)Background: Primary Healthcare (PHC) is often the first point of contact for patients and thus considered the ideal place to address obesity and lifestyle issues. A weight reduction programme was developed to gain a better ... -
A prospective chohort study on bone formation and bone loss in ankylosing spondylitis
(2019-10-02)Background and objectives: Patients with ankylosing spondylitis (AS) have an increased risk of bone loss with development of osteoporosis and vertebral fractures (VFs) but also spinal new bone formation with growth of bony ... -
Abdominal Aortic Aneurysm, aspects on diagnosis and treatment
(2018-11-16)Background An abdominal aortic aneurysm (AAA) is an abnormal widening of the aorta with a risk of rupture if it grows to a large diameter. Rupture ... -
Acromegaly - Mortality, Morbidity and Treatment Patterns
(2022-05-10)Background: Acromegaly is a systemic disease associated with multiple comorbidities. The clinical characteristics of acromegaly develop insidiously over several years and the diagnosis is usually delayed. Progress has been ... -
Actions of androgens and estrogens in experimental models of cardiovascular disease
(2010-10-31)Men are at higher risk of developing both atherosclerotic cardiovascular disease and abdominal aortic aneurysm (AAA). Actions of sex steroids are hypothesized to underlie these gender differences. Testosterone, the major ... -
Activation of professional phagocytes with emphasis on the formyl peptide receptor family
(2009-05-08)Phagocytic cells such as neutrophil granulocytes and monocytes are an essential part of our innate immune system and play an important role in the battle against pathogens. G-protein coupled receptors (GPCRs) and more ... -
Acute coronary syndrome and cardiac arrest in the elderly
(2015-05-11)The elderly are currently the fastest growing segment of clinical practice but the quality and quantity of the underlying scientific evidence to guide treatment is limited. In this thesis five different studies investigating ... -
Acute Coronary Syndromes. Characteristics, management and prognosis in relation to gender and type of syndrome
(2006-12-20)ABSTRACT Background: Acute coronary syndromes (ACS) represent a wide spectrum of conditions from ST-elevation myocardial infarction (STEMI) to unstable angina pectoris (UAP). Randomized trials tend to focus on ST-elevation ... -
Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers
(2013-11-11)Research questions: 1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)? 2 How does myocardial ischemia affect ... -
Adaptation of ventricular repolarization to heart rate change in humans
(2021-10-01)Background: Life-threatening cardiac rhythm disturbances and sudden death are common manifestations of heart disease. Disturbances in electrical recovery (ventricular repolarization; VR) are important mechanisms behind ... -
Adaptive immune maturation in relation to allergic disease and vaccine responses in children
(2017-01-30)Adaptive immune maturation in children is likely the result of a complex interplay between both intrinsic and environmental factors, but surprisingly little is known about how early life immune maturation is related to ... -
Addison's Disease and Type 1 Diabetes Mellitus
(2018-05-18)Background: Patients with type 1 diabetes (T1DM) and patients with Addison’s disease (AD) need life-long replacement therapy with insulin and glucocorticoids (GCs), respectively. Both groups have reduced life-expectancy. ... -
Adherence to lipid-lowering medications and cardiovascular disease prevention in type 2 diabetes mellitus
(2018-11-07)Background and aims: Globally, cardiovascular disease (CVD) is the major cause of death among patients with type 2 diabetes mellitus (T2DM). Improved control of LDL cholesterol with lipid-lowering medications and patients’ ... -
Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
(2013-11-29)Obesity is associated with a low-grade chronic inflammation with increased levels of proinflammatory markers in the circulation and local inflammation in the adipose tissue. In this thesis, two aspects of obesity-related ... -
Airway sensory hyperreactivity linked to capsaicin sensitivity. Definitions and epidemiology.
(2008-08-28)Aims: • To study the relationship between odour intolerance and capsaicin sensitivity and to develop a definition of airway sensory hyperreactivity (SHR). • To study epidemiology of odour intolerance; particularly ... -
Alcohol prevention in Swedish primary health care
(2011-10-11)Abstract Aims: The objectives of this thesis are to describe attitudes among general practitioners (GPs) and district nurses (DN) towards working with risk alcohol drinking and focus on the achievements of the Swedish ... -
Allergic and non-allergic asthma: Translational research in immunology
(2022-05-18)Asthma is a chronic heterogeneous respiratory disease affecting more than 300 million people globally. The different phenotypes, including allergic and nonallergic asthma, are driven by different underlying mechanisms ... -
Analysis of Endogenous Particles in Exhaled Air
(2011-03-25)Exhaled air contains non-volatile particulate material from the respiratory tract. The precise location in which exhaled particles are formed is unknown, and details on their chemical content are scarce. The aim of this ... -
Androgen receptor signaling mechanisms in bone
(2018-12-13)Osteoporosis is a common age-related disease that increases the risk of fractures. Androgens are crucial for bone health in males. Although a substantial part of the effects of androgens on the skeleton is mediated via ...