Doctoral Theses / Doktorsavhandlingar Institutionen för medicin: Recent submissions
Visas titlar 221-240 av 570
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Traumatic episodes related to the genocide period, mental health effects and perceived barriers to care facing young adults in Rwanda
(2016-05-09)Aims: To investigate mental health status in a Rwandan population aged 20-35 years, their associations with traumatic episodes experienced during the 1994 genocide and life time, and barriers to care as perceived by health ... -
Pharmacological stimulation of endothelial function and long-term impact of hypertension in man
(2016-05-06)Background: Ischemic heart disease is a major cause of death globally. Rupture of a coronary atherosclerotic plaque with occluding thrombus formation is the main cause of myocardial ischemia and infarction. A healthy ... -
Epidemiological Aspects of Renal Impairment in Patients with Type 2 Diabetes
(2016-05-04)Diabetes is a leading cause of renal impairment (RI) and indication of the need for renal replacement therapy in many parts of the world. Albuminuria and RI are the two main forms of diabetic kidney disease. The overall ... -
Bleeding tendency and health-related quality of life in carriers of haemophilia
(2016-05-02)Haemophilia A and B are X-linked disorders caused by impaired synthesis of coagulation factors VIII and IX, respectively. Women who carry the haemophilia trait have about 50 % of normal factor levels. Due to skewed ... -
The association between eczema, asthma and rhinitis -population studies of prevalence and risk factors among adults
(2016-04-28)Background: Allergic diseases such as asthma, rhinitis and eczema have increased significantly since the middle of the past century and are now common conditions among both children and adults. The increase was observed ... -
Re-interventions after endovascular aortic repair: clinical and experimental studies
(2016-04-25)Background: Endovascular aortic repair (EVAR) has lower morbidity and mortality than open surgery. Late complications and re-interventions are more common, however, and the timing of different re-interventions and their ... -
Restless legs syndrome among women with chronic widespread pain
(2016-04-25)Aims: The main aim of this thesis was to explore the prevalence, incidence and severity of Restless Legs Syndrome (RLS) in subjects with Chronic Widespread Pain (CWP). In addition, the thesis aimed to analyse the impact ... -
Roles of PI3-kinase and ARAP2 in regulating glucose metabolism
(2016-04-19)Insulin signaling is mediated by a complex, highly integrated network which functions to control multiple metabolic and growth processes throughout the organism. A key enzyme in the insulin signaling network is ... -
Endotoxin-induced inflammation in healthy human airways
(2016-04-11)The aim of this thesis was to investigate the innate immune response in healthy human airways in vivo after simulation of a Gram-negative infection. Intrabronchial exposure to the TLR4 agonist endotoxin was used as a ... -
Obstructive sleep apnea in coronary artery disease: Impact of CPAP treatment
(2016-04-05)Obstructive Sleep Apnea in Coronary Artery Disease: Impact of CPAP treatment Helena Glantz Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, ... -
Biologics in Staphylococcus aureus arthritis
(2016-04-05)The emergence of new type of drugs known as biologics has led to rapid disease improvements in many autoimmune arthritic patients. Nevertheless, most of these biologics are immunomodulators that may consequently increase ... -
Membranous Nephropathy - Challenges in diagnostics and treatment
(2016-04-04)The variability in the pathogenesis, clinical presentation and outcome of membranous nephropathy (MN) poses major clinical challenges and raises different questions, both regarding diagnostics and treatment of patients ... -
Factors influencing prognosis in acute coronary syndrome - A report from the SWEDEHEART registry
(2016-02-25)Background: Acute coronary syndrome (ACS) is one of the major causes of mortality in the world. The prognosis for patients with ACS is affected by several factors, such as baseline characteristics and treatment before, ... -
Cardiovascular and pulmonary health effects of air pollution - long term effects in Sweden and effects of wood smoke
(2016-02-24)Exposure to air pollution is associated with increased morbidity and mortality in cardiovascular and pulmonary diseases. Main suggested mechanisms are airway and systemic inflammation, affecting hemostasis in the short ... -
Gut microbial regulation of bile acid metabolism and signaling
(2016-01-25)The collection of microbes in our gastrointestinal tract, the gut microbiota, is an environmental factor that has profound impact on host health and disease. Bile acids are endogenous cholesterol-derived molecules that can ... -
Surgical management of aortic prosthetic valve endocarditis
(2016-01-25)Background: Infective endocarditis (IE) is still associated with high mortality and morbidity despite advances in diagnostic, medical and surgical management. Aims: I. To report short- and mid-term results after surgical ... -
Reconstruction of the RVOT with a conduit: Lifetime follow up
(2016-01-15)Background: The use of a conduit is an established surgical method for reconstruction of the right ventricular outflow tract in congenital heart disease. The most commonly used conduit is a homograft. Its limited ... -
Challenges in prevention and timely care of uterine prolapse in Nepal
(2015-12-09)Background: Uterine prolapse is a common reproductive health problem in low-income countries like Nepal. Physical symptoms of this condition influence women’s quality of life. Current data insufficiently determine women’s ... -
Physical activity: Prescription in health care and relationship to different health measures
(2015-12-01)Background: Physical inactivity is one of the major modifi able risk factors, contributing to the global burden of disease. Thus, reducing physical inactivity is of importance for global health. Worldwide, different ... -
Prognostic prediction and treatment of cardiac diseases in elderly
(2015-12-01)Aim: The overall aim of this thesis was to study the prognostic prediction and its association with treatment strategies in the elderly patients presenting with acute coronary syndrome (ACS) and left ventricular systolic ...