Browsing Doctoral Theses / Doktorsavhandlingar Institutionen för neurovetenskap och fysiologi by Issue Date
Now showing items 1-20 of 434
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Whiplash-associated disorders from a physical therapy and health-economic perspective. A study of an active physical therapy involvement and intervention for the treatment of acute whiplash-associated disorders and an analysis of its costs and consequences.
(2006-05-31)Whiplash-associated disorders (WAD) resulting from a biomechanical event in motor vehicle collisions is a major cause of suffering and high costs to society. The overall aim of this thesis was to evaluate the ... -
N-acetylaspartate in brain - studies on efflux and function
(2006-10-16)N-acetylaspartate (NAA) is an amino acid derivative present in high concentration in the brain. The function of NAA is still unsettled in spite of 50 years of research. The mainly neuronal synthesis and glial breakdown of ... -
Late Neuropsychiatric Consequences of Stroke in the Elderly
(2006-11-07)Cognitive impairments and depression have considerable impacts on rehabilitation, quality of life and mortality after stroke. The understanding of cognitive and mood impairments in old and, in particular, very old stroke ... -
Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms
(2006-11-08)Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric ... -
Conditional and non-conditional reward-related responses to alcohol - nicotinic mechanisms
(2006-11-14)The mesolimbic dopamine system is believed to mediate the positive reinforcing and rewarding effects of addictive drugs by increasing dopamine levels in its terminal area, the nucleus accumbens (nAc). Nicotinic acetylcholine ... -
Astrocyte metabolism following focal cerebral ischemia
(2006-11-16)Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel. Despite ... -
Progesterone receptor-mediated effects on apoptosis in periovulatory granulosa cells
(2006-11-28)The most common fate of developing ovarian follicles is demise due to a process known as atresia. Regulation of atresia is dependent on the developmental stage of the follicles, resulting in a continuous reduction of the ... -
The Role of Reactive Astrocytes in Brain Ischemia and Neurotrauma
(2006-11-28)Astrocytes are the most abundant cell type in the central nervous system (CNS) and increasing evidence now suggests that they play an active role in various brain functions. Astrocytes are involved in the induction and ... -
Cognitive dysfunction studied in animal models of schizophrenia
(2006-12-01)Cognitive dysfunction is considered a core deficit of schizophrenia, which currently lacks effective pharmacological treatment. In order to identify novel and more effective drug treatments, translational experimental ... -
Language problems at 2½ years of age and their relationship with school-age language impairment and neuropsychiatric disorders
(2007-01-03)Background: International research has shown that language delay (LD) is associated with social, cognitive, emotional and/or behavioural deficiencies, but there is still a need for extended knowledge about LD at early age ... -
Mechanism of Action of the Antiarrhythmic Agent AZD7009
(2007-01-26)Atrial fibrillation (AF) is the most common tachyarrhythmia in the adult population and is a major cause of morbidity and mortality. AF can be terminated and sinus rhythm restored by prolonging the action potential duration ... -
Stroke rehabilitation: A randomized controlled study in the home setting; Functioning and costs.
(2007-01-29)Aim: The purpose of the thesis was to describe and evaluate different aspects of rehabilitation after discharge for persons of working age after stroke. Aims were to compare an approach of support, information and training ... -
Children with autism grow up. Use of the DISCO (Diagnostic Interview for Social and COmmunicative disorders) in population-based cohorts
(2007-02-02)Objectives: Examine the prevalence and outcome of autism in child and adult population cohorts using the Diagnostic Interview for Social and COmmunication disorders (DISCO). Method: The Faroe Islands school population aged ... -
Growth Hormone and Melanin-Concentrating Hormone receptor in the regulation of energy balance and metabolism
(2007-02-12)Energy homeostasis – the balance of energy intake, expenditure, and storage – is controlled by autonomic regulation originating in the hypothalamus and the brain stem, which receive input from the periphery. Upon receiving ... -
Boys with Asperger Syndrome grown up. A longitudinal follow-up study of 100 cases more than 5 years after original diagnosis
(2007-03-09)Introduction and aims: In 1981, the diagnostic label of Asperger Syndrome (AS), was coined after the Austrian paediatrician Hans Asperger, by the English psychiatrist Lorna Wing, who reintroduced his 1944 work about “die ... -
Mass spectrometry based proteomic strategies applied in the study of central nervous system derived cells
(2007-03-26)This thesis focuses on evaluation, improvement and development of mass spectrometry based proteomic strategies for identification and quantitation of proteins. Development of such strategies is important to achieve a better ... -
Orthoptic Findings and Visual Fixation in children in general and in children with surgically treated hydrocephalus
(2007-04-11)Background: The ocular motor system is complex and dependent on the cooperation of many different areas of the brain. Ocular motor functions may be disturbed by various factors resulting in strabismus, and abnormal fixational ... -
Autism syndromes in three behavioural phenotype conditions. A clinical psychiatric study of 76 individuals with Möbius sequence, CHARGE syndrome, and oculo-auriculo-vertebral spectrum
(2007-04-12)AUTISM SYNDROMES IN THREE BEHAVIOURAL PHENOTYPE CONDITIONS A clinical psychiatric study of 76 individuals with Möbius sequence, CHARGE syndrome, and oculoauriculovertebral spectrum Maria Johansson Institute of ... -
Mild stroke - consequences in everyday life, coping and life satisfaction.
(2007-04-25)Abstract Aim: The aim of this thesis was to explore the life situation one year after an apparently mild stroke, and to compare life satisfaction between patients and their spouses. Method: Seventy-five patients with ... -
Imaging of coronary artery function and morphology in living mice - applications in atherosclerosis research
(2007-05-04)Atherosclerosis in the coronary arteries is the major reason for myocardial infarction and cardiovascular death. In the clinic, several imaging systems make it possible to study coronary artery function and morphology ...