Person-centred prehabilitation program to improve functioning
In patients with severe low back pain planned for lumbar fusion surgery
Sammanfattning
Introduction: Low back pain is a frequently reported symptom and has turned into a global
problem. For people with severe chronic low back pain, spinal fusion surgery can be a treatment
option. The outcome of fusion surgery is not always successful and some patients report having
a low quality of life after surgery. The overall purpose of this thesis was to develop and evaluate
a prehabilitation programme for patients scheduled for lumbar fusion surgery. In addition, the aim
was to investigate the pre-surgical level of physical activity in this group.
Material and methods: In Study I, a person-centred prehabilitation programme was developed
in several steps and tested in a single case study design. In Study II, the theoretical framework
and the treatment manual for the active intervention were described in detail in the format of a
study protocol. In Study Ⅲ the physical activity level of 118 patients planned for surgery due to
degenerative disc disease was investigated objectively in a cross-sectional study. An association
between factors in the fear-avoidance model and physical activity were investigated. In Study Ⅳ
the effect of the prehabilitation programme was evaluated in a randomised controlled trial
comparing the active intervention to conventional care. A linear mixed model was used to
evaluate the outcome measures at six months after lumbar fusion surgery.
Results: The theoretical framework and the treatment manual of the prehabilitation programme
were adjusted after the single case study (Study I). The revised study design was published in a
study protocol (Study II). Only 17% of the study group fulfilled the WHO recommendations of
physical activity for health benefits. The variable “steps per day” was found to be associated with
both fear of movement and disability (Study Ⅲ ). No statistically significant differences between
groups were seen in the primary outcome disability from baseline to six months (Study IV).
Among secondary outcome measures, a statistically-significant interaction effect was seen for
EQ-5D index with the largest between-group difference seen one week prior to surgery in favour
of the active intervention. Both groups reached the minimal important change for the primary
outcome, and many of the secondary outcomes already at 8 weeks follow-up.
Conclusion: These findings, indicate that patients planned for lumbar fusion surgery have low
physical activity level and are thereby at greater risk of poor health. A prehabilitation programme
leads to minimal important changes for the primary outcome, and many of the secondary
outcomes already at 8 weeks follow-up.
Delarbeten
I. Lotzke H, Gutke A, den Hollander M, Smeets R, Lundberg M. Developing an evidence-based prehabilitation programme designed to improve functional outcomes after lumbar fusion surgery – A feasibility study using the Medical Research Council framework. European Journal of Physiotherapy. Accepted II. Lotzke H, Jakobsson M, Brisby H, Gutke A, Hägg O, Smeets R, den Hollander M, Olsson L-E, Lundberg, M. Use of the PREPARE (PREhabilitation, Physical Activity and exeRcisE) program to improve outcomes after lumbar fusion surgery for severe low back pain: a study protocol of a person-centred randomised controlled trial. BMC Musculoskelet Disord. 2016;17(1):349 ::doi::10.1186/s12891-016-1203-8 III. Lotzke H, Jakobsson M, Gutke A, Hagströmer M, Brisby H, Hägg O, Smeets R, Lundberg M. Patients with severe low back pain exhibit a low level of physical activity before lumbar fusion surgery: a cross-sectional study. BMC Musculoskelet Disord. 2018; 19(1):365 ::doi::10.1186/s12891-018-2274-5 IV. Lotzke H, Brisby H, Gutke A, Hägg O, Jakobsson M, Smeets R, Lundberg M. A Person-Centered Prehabilitation Program Based on Cognitive-Behavioral Physical Therapy for Patients Scheduled for Lumbar Fusion Surgery – A Randomized Controlled Trial. Submitted
Examinationsnivå
Doctor of Philosophy (Medicine)
Universitet
University of Gothenburg at Sahlgrenska Academy
Institution
Institute of Clinical Sciences. Department of Orthopaedics
Disputation
Fredagen den 18 januari 2019, kl 13.00, sal 2118, Hälsovetarbacken, Arvid Wallgrens Backe, hus 2, plan 1, Göteborg
Datum för disputation
2019-01-18
E-post
hanna.lotzke@gu.se
Datum
2018-12-13Författare
Lotzke, Hanna
Nyckelord
chronic low back pain
cognitive behavioural approach
lumbar fusion surgery
physical activity
person-centred care
prehabilitation
Publikationstyp
Doctoral thesis
ISBN
978-91-7833-267-0 (PRINT)
978-91-7833-268-7 (PDF)
Språk
eng