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Aspects on colostomy construction, complications and stoma function

Sammanfattning
Aim: The aim of this thesis was to evaluate the importance of surgical technique for stoma complications as well as stoma function in patients operated with colostomy. Methods: Five papers are included: Three observational studies (three papers), one randomized control trial (two papers). Clinical data has been collected from medical records, operative notes, the Swedish Colorectal Cancer Registry, prospectively registered clinical records forms and patient reported data through questionnaires. Results: The incidence of stoma related complications is high and may be affected by surgical technique but not stoma function (paper I). Most patients seem to live a full life with their stoma (paper II). A loop colostomy does not seem to reduce the risk for postoperative complications after surgery for obstructing colorectal cancer but it does affect the stoma related complications (paper III). The incidence of parastomal hernia was not affected by the surgical technique used under colostomy construction (paper IV-V). Conclusion: Surgical technique when colostomies are performed influences the occurrence of short-term complications in patients operated with abdominoperineal excision. Parastomal hernia incidence is not affected by the surgical technique used for colostomy construction. Stoma type does not affect the risk for postoperative complications.
Delarbeten
I. Angenete E, Correa-Marinez A, Heath J, Gonzalez E, Wedin A, Prytz M, Asplund D, Haglind E. Ostomy function after abdominoperineal resection- a clinical and patient evaluation. Int J Colorectal Dis. 2012; 27(10): 1267-1274. ::doi::10.1007/s00384-012-1463-1
 
II. Marinez AC, Gonzalez E, Holm K, Bock D, Prytz M, Haglind E, Angenete E. Stoma-related symptoms in patients operated for rectal cancer with abdominoperineal excision. Int J Colorectal Dis. 2016; 31(3): 635-641. ::doi::10.1007/s00384-015-2491-4
 
III. Correa-Marinez A, Grenabo J, Bock D, Wedin A, Angenete E. The type of stoma matters-morbidity in patients with obstructing colorectal cancer. Int J Colorectal Dis. 2018; 33(12): 1773-1780. ::doi::10.1007/s00384-018-3164-x
 
IV. Correa-Marinez A, Erestam S, Haglind E, Ekelund J, Angerås U, Rosenberg J, Helgstrand F, Angenete E. Stoma-Const- the technical aspects of stoma construction: study protocol for a randomized controlled trial. Trials 2014; 15(1): 254. ::doi::10.1186/1745-6215-15-254
 
V. Correa-Marinez A, Bock D, Erestam S, Engström A, Kälebo P, Wirenfeldt Nielsen Y, Rosenberg J, Haglind E, Angenete E. Colostomy construction did not affect parastomal hernia rate: results from Stoma-Const a randomized controlled trial. Manuscript.
 
Examinationsnivå
Doctor of Philosophy (Medicine)
Universitet
University of Gothenburg. Sahlgrenska Academy
Institution
Institute of Clinical Sciences. Department of Surgery
Disputation
Fredagen den 24 maj 2019, kl 9.00, Stora Aulan, Centralkliniken, Sahlgrenska Universitetssjukhuset/Östra, Göteborg
Datum för disputation
2019-05-24
E-post
adiela-adriana.correa-marinez@vgregion.se
URL:
http://hdl.handle.net/2077/59063
Samlingar
  • Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper
  • Doctoral Theses from Sahlgrenska Academy
  • Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Fil(er)
Abstract (166.9Kb)
Thesis frame (2.172Mb)
Cover (1.883Mb)
Datum
2019-04-30
Författare
Correa Marinez, Adiela
Nyckelord
Colostomy
Surgical technique
Stoma related complications
Publikationstyp
Doctoral thesis
ISBN
978-91-7833-419-3 (PDF)
978-91-7833-418-6 (PRINT)
Språk
eng
Metadata
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