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Lumbar Disc Herniation Surgery - Novel Approaches, Timing and Outcomes

Sammanfattning
Lumbar Disc Herniation Surgery – Novel Approaches, Timing and Outcomes JOEL BECK Department of Orthopaedics, Institute of clinical sciences, Sahlgrenska academy, University of Gothenburg, Sweden, 2021 ABSTRACT BACKGROUND Full Endoscopic Lumbar Discectomy (FELD) is a minimal invasive procedure to treat lumbar disc herniation. A description of the clinical introduction in Sweden and a comparison to other surgical methods is a prerequisite before a widespread national introduction. Mental health status and proper surgical timing have been hypothesized to influence the outcomes after lumbar disc herniation surgery and was investigated in a large national cohort. AIM The purpose of the thesis was to introduce FELD to a larger audience, and to gain further knowledge about important predictors for an unsuccessful result after lumbar disc herniation surgery. STUDY POPULATION The study population contain the first 92 patients having a FELD procedure at the Sahlgrenska University Hospital, Gothenburg, Sweden. They were recruited and compared to controls from the Swedish national spine register – Swespine. Preoperative sciatic pain duration and mental health measured by the EQ-5D were examined for 6216 patient having lumbar disc herniation surgery 2013-2017 and patient reported outcomes were analysed. METHODS The introduction of the FELD procedure was described using a cohort of patients from the Sahlgrenska University Hospital. Postoperative patient reported outcomes measures were compared to matched controls. Preoperative duration of sciatica, anxiety and depression as predictive factors of postoperative residual leg pain and disability was studied in lumbar disc herniation patients. RESULTS The Swedish introduction of FELD was described and the postoperative results were compared to patients having standard surgery for lumbar disc herniation. FELD was able to achieve comparable in post-operative leg pain, satisfaction and disability. An extended duration of sciatica was associated with patients reporting inferior outcomes. A significant proportion of patients that state extreme anxiety and depression preoperatively, fail to improve after lumbar disc herniation surgery. CONCLUSION: The FELD procedure can be introduced with similar results to standard surgery for LDH. A prolonged duration of preoperative sciatica leads to a greater risk of achieving dissatisfied patients with a higher level of residual leg pain. Patients that suffer from anxiety and depression are able to reach the same level of quality of life as other lumbar disc herniation patients, but at a higher risk of not improving and expressing disability or residual leg pain. KEYWORDS FELD, Full Endoscopic Lumbar Discectomy, PELD, Percutaneous endoscopic lumbar discectomy, disc herniation, sciatica, pain duration, discectomy, time-to-surgery
Delarbeten
1. Beck J, Westin O, Klingenstierna M, Baranto A. Successful Introduction of Full-Endoscopic Lumbar Interlaminar Discectomy in Sweden. Int J Spine Surg. 2020;14(4):563-570. ::doi::10.14444/7075
 
2. Joel Beck, Olof Westin, Mikael Klingenstierna, Adad Baranto. Full-Endoscopic lumbar discectomy vs standard surgery for lumbar disc herniation - a matched cohort study Submitted
 
3. Beck J, Westin O, Brisby H, Baranto A. Association of extended duration of sciatic leg pain with worse outcome after lumbar disc herniation surgery: a register study in 6216 patients. J Neurosurg Spine. 2021;1-9. ::doi::10.3171/2020.8.SPINE20602
 
4. Joel Beck, Olof Westin, Adad Baranto. Don't back down - Lumbar disc herniation surgery for the depressed and anxious In manuscript
 
Examinationsnivå
Doctor of Philosophy (Medicine)
Universitet
University of Gothenburg. Sahlgrenska Academy
Institution
Institute of Clinical Sciences. Department of Orthopaedics
Disputation
Fredagen den 10 december 2021, kl 9.00, Hjärtats Aula, Sahlgrenska Universitetssjukhuset, Blå Stråket 5, Göteborg
Datum för disputation
2021-12-10
URL:
http://hdl.handle.net/2077/69328
Samlingar
  • Doctoral Theses / Doktorsavhandlingar Institutionen för kliniska vetenskaper
  • Doctoral Theses from Sahlgrenska Academy
  • Doctoral Theses from University of Gothenburg / Doktorsavhandlingar från Göteborgs universitet
Fil(er)
Thesis frame (1.460Mb)
Abstract (704.5Kb)
Cover (1.956Mb)
Datum
2021-11-16
Författare
Beck, Joel
Nyckelord
FELD
Sciatica
Discectomy
Disc Herniation
Full Endoscopic Lumbar Discectomy
PELD
Time-To-Surgery
Pain duration
Percutaneous Endoscopic Lumbar Discetomy
Publikationstyp
Doctoral thesis
ISBN
978-91-8009-518-1 (PRINT)
978-91-8009-519-8 (PDF)
Språk
eng
Metadata
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