Institute of Medicine / Institutionen för medicin: Recent submissions
Now showing items 161-180 of 848
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Mitochondrial dysfunction in juvenile and adult dermatomyositis
(2020-09-28)Introduction Previous studies have shown perifascicular regions in dermatomyositis with mitochondrial abnormalities affecting complex IV also known as cytochrome c oxidase (COX) in the respiratory chain. The aim of this ... -
Enhanced retention of protein damage during ageing
(2020-09-28)Age can be reset in many different cell types through asymmetric cell division. During such a division, retention of aging factors in one cell allows the rejuvenation of the other. In unicellular organisms, it can provide ... -
Immune Checkpoint Receptor Expression in NK Cells
(2020-09-28)Background Immunotherapy for cancer has improved overall survival and revolutionized the field of oncology. Blockade of immune checkpoint receptors has reversed cancer-induced inhibition of T cells and natural killer ... -
Clinical outcome of postchemotherapy retroperitoneal lymph node dissection in advanced nonseminomatous germ cell tumors
(2020-09-28)Background: Nonseminomatous germ cell tumors (NSGCT) which have not responded adequately to chemotherapy requires subsequent surgical removal of the residual tumor (post chemotherapy retroperitoneal lymph node dissection, ... -
Targeted therapy in metastaical melanoma: Clinical evaluation and biomarkers for response
(2020-09-28)BRAF-MEK-inhibition and real world data in metastatic melanoma: Clinical evaluation and biomarkers for response Degree project, programme in medicine, 2018 Christoffer Kvarnström Supervisors: Lars Ny and Henrik Jespersen ... -
A Methodological Study Comparing Two Motor Cortex Plasticity Paradigms in Healthy Adults
(2020-09-28)Background: Neural plasticity is an important function of the brain allowing for change in synaptic transmissions. Modulation in plasticity arises through activity-dependent strengthening; long-term potentiation (LTP), or ... -
Maternal and infant body composition in relation to fish and meat intake during pregnancy - A randomized longitudinal dietary intervention study
(2020-09-23)Introduction: Many women start their pregnancy at a high BMI and gain more weight than recommended during pregnancy, thus increasing the risk for severe pregnancy complications and children born large for gestational ... -
50 år av Hemoglobinnivåer hos kvinnor i Kvinnoundersökningen 1968-1969 till 2016-2017
(2020-09-23)Introduction: Anemia is a global problem and women and children are the most affected. The symptoms of anemia are for example tiredness, dyspnea and headache. Previous studies of trends of anemia over time have not been ... -
Gramnegativ sepsis hos barncancerpatienter i Göteborg; kliniska aspekter
(2020-09-23)Background: Children with cancer or children after stem cell transplantation have an increased risk of neutropenic infections. Previous studies have shown that the incidence of gram-negative bacteraemia has increased in ... -
Completeness of Proximal Humeral Fracture Reoperation
(2020-09-22)Background: The Swedish Fracture Register (SFR) was started in 2011 at Sahlgrenska University Hospital (SUH). Since then, proximal humeral fractures (PHF) have been consecutively registered. Reoperation is considered a ... -
Fever in infants below 2 months of age: clinical management and outcome
(2020-09-22)Title: Fever in infants below 2 months of age: clinical management and outcome Degree Project in Medicine, Programme in Medicine, Sahlgrenska Academy at the University of Gothenburg, Sweden 2019. Author: Michelle Bäckman ... -
Associations between ECG abnormalities and death or myocardial infarction. A 25 year follow up of middle-aged men employed in a Swedish automotive industry
(2020-09-22)Background: The Coeur Project started in 1992 as a joint medical project between two automotive companies, one located in Sweden (the Volvo Corporation) and one located in France (Renault Automotive Group). The original ... -
Long-Term Outcomes of Percutaneous Radiofrequency Ablation of Small Renal Tumours
(2020-09-22)Background: Ablation technique is relatively new nephron-sparing treatment of small renal masses (SRM). It carries a lower complication rate and lower overall healthcare costs compared with surgery. However, there are ... -
Risk Factors for Harmful Alcohol Consumption Among University Students in Hanoi
(2020-09-22)Background: Excessive alcohol consumption is a risk factor for many non-communicable diseases and is considered an important target in reaching the sustainable development goals set by the UN. In Vietnam, alcohol consumption ... -
Colorectal cancer in a Sri Lankan teaching hospital
(2020-09-22)Degree Project, Programme in Medicine, Colorectal cancer in a Sri Lankan teaching hospital, Sofia Lindskogen, 2020, Department of Surgery, University of Gothenburg, Sweden. Background: The economy in Sri Lanka has improved ... -
Penetrating Pediatric trauma; how physiological parameters and management of children differs from an adult population
(2020-09-22)Background: There is a growing need for knowledge to manage children with penetrating trauma as securely and correctly as adults. Firstly, pediatric vital parameters are age-specific and therefore differ from the adults. ... -
Semiology and Classifications of Paediatric Psychogenic Nonepileptic Seizures – a Systematic Review
(2020-09-22)Introduction: One of the main differential diagnoses of epilepsy is psychogenic nonepileptic seizures(PNES). The presentation of symptoms are paroxysmal events of motor, non-motor, behavioural and subjective characteristics. ... -
Evidence for education and advice in patients with chronic pain - A Systematic and analytic literature study
(2020-09-22)Background In Europe approximately 20 % of the population suffers from chronic pain. Chronic pain affects both individuals and society negatively. Multimodal rehabilitation (MMR) is effective as treatment for chronic pain ... -
Freeze-Dried Plasma and Adverse Events
(2020-09-22)Introduction: Freeze-dried plasma (FDP) is a pulverized form of blood plasma. FDP has many advantageous characteristics and can be used to correct coagulopathy or as a volume expander. Packed red blood cells (PRBC) are ... -
Telomerase Reverse Transcriptase protein expression as prognostic factor
(2020-09-22)Introduction: Glioblastoma (GBM) is the most common malignant primary tumor of the central nervous system in the adult male. The average survival is between 3 and 5 months without treatment, and between 9 and 15 months ...