Doctoral Theses / Doktorsavhandlingar Institutionen för medicin: Recent submissions
Now showing items 321-340 of 570
-
Vascular Function in Chronic Renal Failure
(2014-02-21)A majority of patients with chronic kidney disease (CKD) die of cardiovascular (CV) disease before reaching end-stage renal disease. The causes of CV death in CKD are characterized by an excess of sudden cardiac deaths ... -
Children's hypersensitivity to cow's milk - Public health aspects and impact on families
(2014-02-17)Background and aims: Diet during childhood can have lifelong consequences for health. Cow’s milk is regarded as a basic food item in Sweden, but is also the most usual cause of adverse reactions during the first years of ... -
Elevated calcium concentration, is it dangerous? Long-term follow-up in primary care
(2014-02-12)Background and aims: Patients with hypercalcaemia are relatively common in primary care; the most frequent causes are primary hyperparathyroidism (pHPT) and cancer. Many patients with pHPT have such discrete symptoms that ... -
Barriers and Facilitators of Health Promotion and Obesity Prevention in Early Childhood: A Focus on Parents Results from the IDEFICS Study
(2014-02-10)Background: Childhood obesity has increased dramatically during the past thirty years. Parents are key persons in their children’s lives and their efforts to create healthy lifestyles are very important. However, social ... -
Sex hormones and cardiovascular risk in men and women. The Skaraborg Project
(2014-02-04)The general aim of this thesis was to explore the associations between sex hormones and high blood pressure in men and women and to investigate their further role in the development of acute myocardial infarction particularly ... -
Complementary treatment and markers in inflammatory bowel diseases
(2014-01-31)Complementary Treatment and Markers in Inflammatory Bowel Diseases Maria Pagoldh Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden Aims: ... -
Gut bacteria, regulatory T cells and allergic sensitization in early childhood
(2014-01-24)The hygiene hypothesis postulates that reduced or altered microbial exposure early in life may lead to impaired immune maturation and, as consequence of this, development of allergic disorders. Thus, we examined if the ... -
Tyrosine kinase Flt3/Flt3-ligand signaling in the modulation of immune responses in experimental arthritis
(2014-01-13)Rheumatoid arthritis (RA) is an autoimmune, chronic systemic inflammatory disorder that primarily affects flexible joints resulting in severe joint destruction and disability if left untreated. Today, advances in treatment ... -
Intercellular communication via exosomes
(2014-01-08)Exosomes are small membrane bound vesicles between 30-100 nm in diameter of endocytic origin that are secreted into the extracellular environment by many different cell types. They play a role in intercellular communication ... -
Sex steroid hormones - roles in adaptive immunity and vascular pathology
(2013-12-20)The prevalence of autoimmune diseases is higher in women than men, while for cardiovascular disease, there is a male predominance. The sexual dimorphism of autoimmune and cardiovascular diseases probably relates to a number ... -
Monitoring of coagulation and platelet function in paediatric cardiac surgery
(2013-12-10)Abstract Background: Paediatric cardiac surgery has developed dramatically during the last decades. Today, a wide range of patients is operated on-from premature neonates to grown up children with congenital heart disease. ... -
Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
(2013-11-29)Obesity is associated with a low-grade chronic inflammation with increased levels of proinflammatory markers in the circulation and local inflammation in the adipose tissue. In this thesis, two aspects of obesity-related ... -
Developmental and cholera toxin-induced alterations in the expression of intracellular signalling molecules
(2013-11-27)The innate immune system represents the first line of host defence that reacts promptly to attacks by microbes. This system relies on several families of pathogen-recognition receptors (PRRs), which recognize pathogen-associated ... -
Quality of life assessment in patients with lung cancer. Clinical implications
(2013-11-22)Quality of life assessment in patients with lung cancer Clinical implications Mercedes Nicklasson Department of Internal Medicine and Clinical Nutrition/ Respiratory Medicine, Institute of Medicine Sahlgrenska Academy ... -
Shoulder function and activity limitations in patients with early rheumatoid arthritis
(2013-11-22)Patients with rheumatoid arthritis (RA) have impaired physical function which can lead to difficulties with daily activities. Despite improved pharmacological treatment, patients with early RA report difficulties with ... -
Work capacity and mental health - the phenomena and their importance in return to work
(2013-11-22)ABSTRACT Mental health problems are common and a major cause of decreased work capacity and sickness absence. The aim of this thesis was to investigate (i) work capacity and mental health problems as predictors of return ... -
Neutrophil function in health and disease - role of intracellular radicals and galectin-3 as regulators of inflammation
(2013-11-14)The focus for this PhD project has been to investigate neutrophil functions in different (inflammatory) settings with specific focus on phagocyte-derived intracellular reactive oxygen species (ROS) as well as neutrophil ... -
Acute coronary syndromes. The prognostic importance of hypertension, diabetes and vectorcardiographic markers
(2013-11-11)Research questions: 1 Is hypertension and diabetes associated with the future risk of death, and recurrent manifestations of cardiovascular disease in acute coronary syndromes (ACS)? 2 How does myocardial ischemia affect ... -
Plasma coagulation in cardiac surgery
(2013-11-04)Background: Cardiac surgery using cardiopulmonary bypass is a complex procedure, sometimes accompanied with excessive bleeding. The nature and pathophysiology of this bleeding is multifactorial and not completely understood. ... -
Quantitative analysis of bone scans in prostate cancer patients
(2013-10-25)Prostate cancer (PCa) is one of the most common diseases in the world. PCa can primarily disseminate to the bone, causing bone metastases, which in turn can lead to death. It is important to diagnose bone metastases as ...