Doctoral Theses / Doktorsavhandlingar Institutionen för medicin: Recent submissions
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Diabetes and hypertension - entangled chronic conditions in primary care. Time trends and determinants for mortality and cardiovascular complications.
(2021-03-23)Diabetes and hypertension are chronic, often coexisting conditions with increased risk of premature death and cardiovascular complications. This thesis aimed to study different epidemiological aspects regarding risk of ... -
Obesity in diabetes. Cardiovascular outcomes and risk factor trajectories
(2021-03-23)Introduction: The association between body mass index (BMI) and mortality in diabetes is complex and sparsely investigated for cardiovascular (CVD) outcomes. We aimed to investigate these relationships among patients ... -
Patient Assessment and Triage in Emergency Medical Services - The Swedish EMS nurse in a new role
(2021-03-16)Abstract Background: Pre-hospital care is highly complex care where the emergency medical services (EMS) nurse assesses patients in an unselected patient population. The increased demand for EMS resources, which ... -
The role of MBOAT7 on fatty liver disease
(2021-02-18)Non-alcoholic fatty liver disease (NAFLD) is the main health disorder in internal medicine, affecting one third of the population worldwide. Environmental and genetic factors contribute to NAFLD susceptibility and progression. ... -
Neutrophil Function and Signaling Induced by Ligands for the Formyl Peptide Receptor 2
(2021-02-15)Neutrophil pattern recognition receptors belonging to the G-protein coupled receptor (GPCR) family play a role in the processes of initiation as well as resolution of inflammatory processes. Formyl peptide receptor 2 (FPR2) ... -
Price sensitivity and regional variation in health care
(2021-02-12)Understanding the consequences of current health policy is important in order to design and develop a health care system suitable for future challenges. The purpose of this thesis is to bring evidence on the determinants ... -
Pregnancy in women with congenital heart disease
(2021-01-29)Abstract Background: The survival for children born with congenital heart disease (CHD) has increased and the majority reach adult age. Having a cardiac problem raise questions on the probability of successful pregnancies ... -
Learning aspects of out-of-hospital cardiac arrest and learning activities in basic life support - a study among laypersons at workplaces in Sweden
(2021-01-29)Abstract Background: Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of death worldwide. Despite healthcare improvements, prevention for cardiovascular health, training in adult basic life support (BLS) ... -
Irritable bowel syndrome - a disorder of gut-brain interaction
(2021-01-22)Irritable bowel syndrome (IBS) is a common and multifactorial functional gastrointestinal (GI) disorder characterized by altered gut-brain communication. Due to the complexity of gut-brain interactions, the aim of this ... -
Cost-Effectiveness of Vaccination and the Value of Prevention
(2020-11-27)The overall aim of this thesis was to analyse the cost-effectiveness of vaccination of infectious diseases and to investigate the value of prevention, in a Swedish setting. This thesis consists of five studies. In Study ... -
Exposure to household air pollution among women and children in Ethiopia: Socio-cultural factors and the association with airway health
(2020-11-27)Abstract Using solid fuel generates emissions of many health-damaging pollutants including inhalable fine particulate matter (PM2.5). Such exposure is known to cause morbidity and mortality in low- and middle-income ... -
A prevention and health promotion programme for persons with overweight in Primary Health Care Patient outcomes and nurses’ experiences in terms of weight, lifestyle, health and risk factors
(2020-11-20)Background: Primary Healthcare (PHC) is often the first point of contact for patients and thus considered the ideal place to address obesity and lifestyle issues. A weight reduction programme was developed to gain a better ... -
Pituitary Tumors - Epidemiology and the Diagnostic Value of 68Ga-DOTATOC PET
(2020-11-20)Pituitary neuroendocrine tumors (PitNETs) are considered common in the general population. However benign in most cases, these tumors can evoke dramatic morbidity in patients with aggressive tumor growth and/or excess ... -
Aspects of fracture prevention - The role of fracture liaison services and alendronate
(2020-11-05)Objective: In an ageing population, osteoporotic fractures become more common and cause increased morbidity, mortality and societal cost. This thesis aimed to determine the potential role of fracture liaison services (FLS) ... -
Dietary intake, nutritional status and energy metabolism in adolescents with severe obesity - Effects of gastric bypass surgery
(2020-11-02)Background and aims: Roux-en-Y gastric bypass is an effective obesity treatment in adults and is becoming established in adolescents. Information is scarce on long-term changes in dietary intake, nutritional status and ... -
Lipoproteins in Staphylococcus aureus infections
(2020-09-04)Staphylococcus aureus (S. aureus) infections remain a major challenge for the healthcare system, and new treatment options are highly demanded. S. aureus is a pathogenic microorganism, responsible for a broad range of ... -
Aplastic anemia - a population-based study of epidemiology, treatment, and prognostic factors
(2020-09-03)Background and aims. Aplastic anemia (AA) is a rare but life-threatening disease. The introduction of immunosuppressive treatment (IST) and hematopoietic stem cell transplantation (HSCT) has considerably improved the outcome ... -
Pathophysiology and treatment of Takotsubo Syndrome - insights from preclinical studies
(2020-09-03)ABSTRACT Background: Takotsubo syndrome (TTS), also recognized as “stress-induced cardiomyopathy (SIC)” and “broken heart syndrome”, is an acute cardiac failure syndrome characterized by transient regional ventricular ... -
The fight against time in prehospital cardiac arrest - a true medical emergency
(2020-08-18)ABSTRACT Background: The chances of survival after an out-of-hospital cardiac arrest (OHCA) are one in ten. The majority of survivors have no or relatively mild neurological sequelae. Interventions are time critical and ... -
Obesity, Weight Loss and Cardiovascular Risk
(2020-05-26)Background: The global prevalence of obesity is on the rise, contributing to increased incidence and prevalence of cardiovascular morbidity and mortality. Obesity has adverse effects on cardiac structure and function, ...