Doctoral Theses / Doktorsavhandlingar Institutionen för medicin: Recent submissions
Now showing items 161-180 of 570
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Population-Based Long-Term Follow-up of Patients with Myeloproliferative Neoplasms, complications and prognosis
(2018-01-24)ABSTRACT Philadelphia chromosome negative myeloproliferative neoplasms (Ph-MPNs) are rare clonal hematological malignancies, mainly including polycythemia vera (PV), essential thrombocythemia (ET) and myelofibrosis (MF). ... -
Type 1 diabetes in adults: modern treatment and risk of major coronary events
(2018-01-22)Background: According to the National Diabetes Register (NDR) report (2016), 21.2% of adults with type 1 diabetes (T1D) achieve glycaemic targets measured with HbA1c (52 mmol / mol) and 20.1% of patients have very poor ... -
The physician and the sickness certification
(2018-01-18)Background and aims: Sickness insurance is a hallmark of most welfare states. The rising costsof sickness insurance in Sweden have been attributed to varying sickness certification practices among physicians. Other factors, ... -
Safety leadership in the construction industry
(2018-01-02)The overall aim of this thesis was to identify and describe essential components of safety leadership behavior in the construction industry in Sweden and Denmark. The methods used were semi-structured interviews, cross-sectional ... -
On viral infections in lung transplant recipients
(2017-12-15)Viral infections are the most common type of infection in humans. Lung transplantation (LTx) recipients are exceptionally susceptible to infections in general, and the short- and long- term effects tend to be more detrimental. ... -
Immunological and Microbiological perspectives on Irritable Bowel Syndrome.
(2017-11-24)Abstract Irritable bowel syndrome affects ~11% of the population in the Western world and is characterised by altered bowel habits and abdominal pain. The range of additional symptoms between subjects makes groups of ... -
Fitness, cognition and cardiovascular disease. Epidemiological studies.
(2017-11-23)Abstract Physical activity and fitness have well established health bringing benefits. Low soci-oeconomic status is a known risk factor for cardiovascular disease. This association is commonly attributed to individual ... -
The IL-23 axis and innate immunity in the airways
(2017-11-08)The Interleukin-23 (IL-23) axis is a communication system that integrates innate and adaptive immunity. When triggered by microbial stimuli, antigen presenting cells can secrete the cytokine IL-23, leading to the production ... -
STK25- a new key regulator of metabolic profile and a possible target for anti-diabetic drug
(2017-11-02)Type 2 diabetes (T2D) affects at least 285 million people worldwide and its prevalence is rapidly increasing. Understanding the molecular mechanisms controlling ectopic lipid deposition and insulin response in metabolic ... -
Fibrinogen, platelet and factor XIII supplementation in cardiac surgery: In vitro and in vivo studies
(2017-11-02)Background: There is a high risk of bleeding complications in cardiac surgery. Fibrinogen and platelet concentrates are often used to treat perioperative bleeding, but there is little information about its efficacy. The ... -
Modulation of Receptor Signaling and Functional Selectivity in Neutrophils
(2017-10-17)Neutrophils are important effector cells of the innate immune system and in the regulation of inflammation. Many of their functions, such as chemotactic migration, secretion of granule constituents and activation of the ... -
Symptomatic Carotid Stenosis - optimal timing of surgical treatment
(2017-10-17)Abstract In patients with symptomatic carotid artery stenosis is convincing evidence that carotid endarterectomy (CEA) confers maximum benefit if performed within 14 days from index event. Patients with TIA or minor stroke ... -
Diets of European children, with focus on BMI, well-being, and families The IDEFICS/I.Family cohort
(2017-09-28)The overall aim of this thesis was to investigate children’s diet, BMI z-score, and parental feeding practices (PFPs), in relation to mutans streptococci (MS) count, psychosocial well-being and children’s BMI trajectory, ... -
The impact of railway vibration and noise on sleep
(2017-09-25)Sleep is a vital component of good health, and sleep loss is associated with impaired cognition, decreased psychomotor performance, cardiovascular disease, adverse effects on endocrine and metabolic function, negative mood, ... -
Prevalence and treatment of patients with heart failure with special emphasis on diuretics
(2017-09-21)Background: Heart failure (HF) is a major health problem worldwide with an estimated prevalence of about 1-2% in the Western world. The temporal trend for prevalence of HF has never been investigated in a nationwide ... -
Skilled birth attendant services in Nepal: overcoming barriers to utilization
(2017-05-18)Background Skilled birth attendants (SBAs) provide important services that improve maternal and newborn health and reduce maternal and newborn mortality. Utilization and coverage of SBA services reveal wide disparities ... -
Cardiovascular risk factors in renal artery stenosis
(2017-05-11)Renovascular hypertension (RVH) caused by atherosclerotic renal artery stenosis (ARAS) is one of the most common forms of secondary hypertension. The prognosis for patients with RVH is much worse compared to patients ... -
Bone Morphogenetic Protein 4 regulates white, beige and brown adipose tissue
(2017-05-10)Obesity and its associated complications, including Type 2 diabetes, are increasing at an epidemic rate globally. Adipose tissue exerts different functions and is central in energy homeostasis, and it consists of white, ... -
Early childhood thymectomy - impact on immune function
(2017-05-10)Introduction: The thymus is the site of T cell maturation. Children born with a congenital heart defect often endure surgery early in life, and during surgery their thymus is routinely removed, as it blocks the surgeons ... -
Läkare som handledare i klinisk praktik för läkarstudenter. Kunskaper och erfarenheter.
(2017-05-08)Background and aim. Clinical tutors and work place learning are essential resources in modern undergraduate medical education. The aim of this thesis is to increase the knowledge of physicians’ perspective when serving as ...